Vitamin B3 (Calcium D-pantothenate, Calpan, D-Calpan) is a feed additive for the production of compound feeds and premixes for farm animals, including poultry. It is used for enrichment and balancing of feeding diets with pantothenic acid.
Role and Functions of Vitamin B3
The most significant derivative of pantothenic acid is Coenzyme A (CoA). It is in this form that pantothenic acid performs its specific function in metabolism. Coenzyme A plays a fundamental role in:
- General metabolism: It participates in numerous metabolic pathways, including the synthesis and breakdown of carbohydrates, fats, and proteins.
- Protein metabolism: CoA is an active part of many enzymes involved in protein synthesis and degradation.
- Oxidative breakdown and breakdown of fatty acids: It is a key element in the process of generating energy from fats.
- Glucose utilization: CoA is necessary for the efficient use of glucose as an energy source.
- Biosynthesis of steroids: It plays an important role in the production of steroid hormones and cholesterol, which are essential for many physiological functions.

Interrelation with Other Vitamins and Consequences of Deficiency
The biological role of Vitamin B3 is closely linked to the metabolism of other B-group vitamins, highlighting their synergistic action in the body. A deficiency of pantothenic acid can lead to serious disorders, including:
- Skin dermatitis: Inflammatory skin lesions.
- Necrosis of the large intestine: Tissue death in the large intestine.
- Impaired coordination of movements: Nervous system problems affecting balance and movement.
- Disruption of fat and water metabolism: This can cause functional disorders of the endocrine system and internal organs, leading to systemic health issues.
- Reduced tryptophan synthesis: Tryptophan is an essential amino acid and a precursor for the synthesis of niacin (another form of Vitamin B3) and serotonin.
Feed Grade Vitamin B3: Application and Compatibility
Feed grade Vitamin B3 is a supplement containing no less than 98.0% calcium pantothenate, obtained through chemical synthesis. In appearance, it is a white powder with a slight specific odor. It’s important to note that this product does not contain genetically modified organisms.
This supplement is specifically designed for the production of premixes and compound feeds for pigs and poultry. Feed grade Vitamin B3 is incorporated into premixes, compound feeds, and feed mixtures at feed mills and premix plants or on-farm feed preparation units, using existing step-by-step mixing technologies to ensure uniform distribution.
When feed grade Vitamin B3 is used in the recommended quantities, no adverse reactions or complications have been observed. It is compatible with all feed ingredients, medicinal products, and other feed additives, making it safe and convenient to use. No contraindications have been identified.
Active ingredient: Calcium D-pantothenate, calcium pantothenate.
Content — 98–99%.
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